Clotrimoxazole (clotrimazole) comes as a cream, lotion, and solution to be applied to the skin; lozenges (called troches) to dissolve in the mouth; and vaginal tablets and vaginal cream to be inserted into the vagina.

Clotrimoxazole is usually used five times a day for 14 days for oral thrush, twice a day (in the morning and evening) for 2 to 8 weeks for skin infections, and once a day at bedtime for 3 or 7 days for vaginal infections.

Follow the directions on the package or your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. It is strongly advised that you use clotrimoxazole exactly as directed, and do not use more or less of it - or use it more often - than prescribed by your doctor.

To use the topical cream, lotion, or solution, thoroughly clean the infected area, allow it to dry, and then gently rub the medication in until most of it disappears. Use just enough medication to cover the affected area. You should wash your hands after applying the medication.

The lozenges should be placed in the mouth and dissolved slowly over about 15 to 30 minutes. Do not chew or swallow the lozenges whole.

To use clotrimoxazole vaginal cream or vaginal tablets, read the instructions provided with the medication and follow these steps:

1. Fill the special applicator that comes with the cream to the level indicated or unwrap a tablet, wet it with lukewarm water, and place it on the applicator as shown in the instructions that come with the product.

2. Lie on your back with your knees drawn upward and spread apart.

3. Insert the applicator high into your vagina (unless you are pregnant), and then push the plunger to release the medication. If you are pregnant, insert the applicator gently. If you feel resistance (hard to insert), do not try to insert it further. You should consult your doctor.

4. Withdraw the applicator.

5. Discard the applicator if it is disposable. If the applicator is reusable, pull it apart and clean it with soap and warm water after each use.

6. Wash your hands promptly to avoid spreading the infection.

The vaginal cream or tablets should be applied just before going to bed. The drug works best if you do not get up again after applying it except to wash your hands. You may wish to wear a sanitary napkin while using the vaginal cream or tablets to protect your clothing against stains. Do not use a tampon because it will absorb the drug. Do not douche unless your doctor tells you to do so.

Continue to use clotrimoxazole (clotrimazole) even if you feel well and please do not stop using clotrimoxazole without talking to your doctor. Moreover, make sure you continue using this medication during your menstrual period.

If you obtained the clotrimoxazole skin cream, lotion, or solution without a prescription, use it for 4 weeks for athlete's foot and 2 weeks for jock itch or body ringworm. If your symptoms do not improve by that time, stop using the medication and consult either a pharmacist or doctor.

 

FDA Information

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