Clotrimoxazole (clotrimazole) is an antifungal medication commonly used in the treatment of fungal infections of both humans and animals such as vaginal yeast infections and ringworm. It is also used to treat athlete's foot and jock itch.

Mechanism of Action:

This medicine kills fungi and yeasts by interfering with their cell membranes. It works by stopping the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol disrupts the cell membrane and causes holes to appear. The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. As clotrimoxazole (clotrimazole) causes holes to appear in the cell membranes, essential constituents of the fungal cells can leak out. This kills the fungi.

 

FDA Information

Other uses for this medicine

Dosage and using this medicine

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In case of an emergency/overdose